A woman, 32 years old, married, consulted about pustular acne. – before menstruation, in the summer; painful; – from fatty foods, meat; – from cold lotions. Suffering from migraine for five years; – from noise, light, exposure to the sun, night shifts, – from tight dressings, in the dark. Mind: Touchy. Thinks about past unpleasant incidents. Anger, from minor contradictions, from comfort. Selfish. Anamnesis – without features. Family history – diabetes, asthma, rheumatoid arthritis. Discussion: The patient has increased susceptibility and sensitivity – this is evidenced by multiple provocative factors, an abundance of physical and mental characteristics. The dominant and fundamental miasm is sycosis. There was no suppression. The total supply of vitality is good. Speed ​​is gradual. Likeness is good. Consequently, infrequent repetitions of Natrum carbonicum 200. The patient received 3 doses of Natrum carbonicum 200 within two years. Local susceptibility (at the level of headache) is also increased. Therefore, for migraine attacks received Glonoinum 200 with frequent repetition until the reaction is achieved. Improved in all respects. A boy, 10 years old, appealed about the mental retardation, epilepsy. He received antiepileptic drugs for six years. Based on the combination of symptoms, Bufo 30 was appointed with frequent recurrence, then Bufo 200. An improvement in mental functions was noted. Epileptic seizures stopped amid Bufo. Discussion: Epilepsy means hyperactivity of the brain; mental retardation means hypoactivity. However, a general assessment indicates a decrease – poverty characteristics, hypoactivity and prolonged antiepileptic treatment. Therefore, the 30th potency is prescribed with repetitions in the initial phase of treatment. The resumption of symptoms meant that the action of the 30th potency was over, so the 200th potency was prescribed. A 30-year-old man is diagnosed with malaria. He noted severe chills, followed by fever and sweating, worsening from 2:00 to 5:00. A trembling chill with anxiety, motor restlessness, could not find a place in bed. Thirst intensified. Arsenicum album 1M was prescribed every 2 hours – this cured the patient. Subsequently, he noted pronounced prostration, for which Carbo vegetabilis 200 was prescribed with frequent repetition. Discussion: The patient’s condition worsened due to an intensively developing disease – this means an increase in susceptibility. Corresponding to this susceptibility is the high potency of the drug with frequent repetition. The convalescence state was also characterized by high susceptibility, therefore, frequent repetitions of Carbo vegetabilis were prescribed.